Oxidative stress biomarkers in organs of hyperlipidaemic and normal rats fed tropical red seaweed, Gracilaria changii

Pei , Teng Chan and Patricia @ Patricia Clementina Matanjun, and Suhaimi Md Yasir, and Tan, Tek Song (2015) Oxidative stress biomarkers in organs of hyperlipidaemic and normal rats fed tropical red seaweed, Gracilaria changii. Journal of Applied Phycology, 27 (4). pp. 1-8. ISSN 0921-8971 (Print) 1573-5176 (Online)

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Official URL: http://dx.doi.org/10.1007/s10811-015-0670-x

Abstract

The aim of the study was to evaluate the effects of normal and high-cholesterol/fat diet supplemented with 5 and 10 % freeze-dried red seaweed, Gracilaria changii powder on rat organs (liver, kidney and heart), lipid peroxidation and antioxidant enzyme activities. The results showed that feeding with atherogenic diet alone caused lipid peroxidation which eventually leads to oxidative stress of the rat’s organs. Nevertheless, with 10 % G. changii supplementation, it significantly decreased the liver lipid peroxidation by 52.24 %, and the antioxidant enzyme activities were significantly increased by 52.09 to 94.42 %. Similarly, with G. changii supplementation, it significantly enhanced the kidney antioxidant enzyme activities. This suggests that G. changii suppress oxidative stress and protect the rats’ organs. In conclusion, G. changii could be a promising functional food ingredient in the management of hyperlipidaemia.

Item Type:Article
Uncontrolled Keywords:Lipid peroxidation, Enzymes antioxidants, Hyperlipidaemic, Red seaweed
Subjects:T Technology > TP Chemical technology
Divisions:FACULTY > Faculty of Food Science and Nutrition
ID Code:12417
Deposited By:IR Admin
Deposited On:02 Dec 2015 14:34
Last Modified:02 Dec 2015 14:34

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