Non-halogenated new sesquiterpenes from Bornean Laurencia snackeyi

Takashi Kamada, and Charles Santhanaraju Vairappan, (2016) Non-halogenated new sesquiterpenes from Bornean Laurencia snackeyi. Natural Product Research: Formerly Natural Product Letters, 31 (3). pp. 333-340. ISSN 1478-6419 (Print), 1478-6427 (Online)


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Two new non-halogenated sesquiterpenes, snakeol (1) and snakediol (2) were isolated together with 9 known sesquiterpenes such as (R,Z)-33-dimethyl-5-methylene-4-(3-methylpenta-24-dien-1-yl)cyclohex-1-ene (3), palisol (4), pacifigorgiol (5), palisadin D (6), palisadin A (7), palisadin B (8), 5-acetoxypalisadin B (9), debromolaurinterol (10) and α-bromocuparane (11) from the red algae Laurencia snackeyi. The structures of two new metabolites were determined from their spectroscopic data (IR, 1D and 2D NMR and MS). Compounds 1, 2, 10 and 11 showed strong antibacterial activity against selected human clinical bacterial pathogens.

Item Type:Article
Uncontrolled Keywords:Laurencia snackeyi; Red alga; antibacterial activity; chemical race; rhodomelaceae; sesquiterpene
Subjects:Q Science > QD Chemistry
Divisions:SCHOOL > Institute for Tropical Biology and Conservation
ID Code:15446
Deposited By:Munira M
Deposited On:31 Jan 2017 14:32
Last Modified:31 Jan 2017 14:32

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