A new seco-clerodane-type diterpenoid from Bornean liverwort Schistochila acuminate

Ng, Shean Yeaw and Takashi Kamada and Monica Suleiman and Charles Santhanaraju Vairappan (2016) A new seco-clerodane-type diterpenoid from Bornean liverwort Schistochila acuminate. Natural Product Communications, 11 (8). pp. 1071-1072. ISSN 1934-578X

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Abstract

A new compound, schistochilic acid D (1) and two known compounds (2 and 3) were isolated from MeOH extract of Bornean liverwort Schistochila acuminata collected from Mount Trus Madi, Sabah. The structure of the new metabolite was established based on spectroscopic (1D NMR, 2D NMR, and IR). And HRESIMS data. In addition, another population of S. Acuminata collected from Mount Alab (Sabah) yielded four known compounds, 2, 3, 4 and 5. These compounds were tested for their biological potential against the B16-F10 cell line. Compounds 4 and 5 exhibited weak cytotoxic activity.

Item Type: Article
Uncontrolled Keywords: Borneo, Chemotype, Cytotoxic, Diterpenoid, Liverwort, Schistochila acuminate
Subjects: Q Science > QH Natural history
Divisions: SCHOOL > Institute for Tropical Biology and Conservation
Depositing User: Munira
Date Deposited: 18 Feb 2018 11:55
Last Modified: 25 Jun 2020 11:16
URI: http://eprints.ums.edu.my/id/eprint/18635

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