The effect of malathion on the activity of cholinesterase from the freshwater Shrimp Caridina sp.

Mohd Khalizan Sabullah, and Fisal Ahmad, and Baskaran Gunasekaran, and Abdul Rahim Abdul Rachman, and Lee, Shi Yin and Siti Aqlima Ahmad, and Mohd Yunus Shukor, and Azlan Jualang Gansau, and Mohd Rosni Sulaiman, (2014) The effect of malathion on the activity of cholinesterase from the freshwater Shrimp Caridina sp. Bulletin of Environmental Science and Management, 2 (2). pp. 36-38.

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Abstract

Acetylcholinesterase (AChE) from Caridina sp. was tested for its sensitivity towards the anticholinesterase malathion. Prior to this study, optimal assay conditions were determined to be 25 oC, pH 8.0 and using phosphate buffer. At 10-8 M, malathion was able to inhibit AChE activity at 1.75% and this increased to 15.79% with the increasing of malathion concentration to 10-4 M. It is proven through this study that the crude extract of AChE is sensitive toward malathion exposure and provide an alternative source for biosensor development.

Item Type: Article
Uncontrolled Keywords: acetylcholinesterase , malathion , Caridina Sp.
Subjects: Q Science > QH Natural history
Divisions: FACULTY > Faculty of Science and Natural Resources
Depositing User: Noraini
Date Deposited: 09 Feb 2018 07:17
Last Modified: 09 Feb 2018 07:17
URI: http://eprints.ums.edu.my/id/eprint/18738

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