High prevalence of alpha- and beta-thalassemia in the kadazandusuns in east Malaysia : Challenges in providing effective health care for an indigenous group

J. A. M. A. Tan, and Lee, Ping-Chin and Yong , Chui Wee and Kim, Lian Tan and Noor Fadzlin Mahali, and D. George, Elizabeth and Kek, Heng Chua (2010) High prevalence of alpha- and beta-thalassemia in the kadazandusuns in east Malaysia : Challenges in providing effective health care for an indigenous group. Journal of Biomedicine and Biotechnology, 2010 (706872). ISSN 1110-7243

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Official URL: http://dx.doi.org/10.1155/2010/706872

Abstract

Thalassemia can lead to severe transfusion-dependent anemia, and it is the most common genetic disorder in Malaysia. This paper aims to determine the prevalence of thalassemia in the Kadazandusuns, the largest indigenous group in Sabah, East Malaysia. - and -thalassemia were confirmed in 33.6 and 12.8, of the individuals studied respectively. The high prevalence of - and -thalassemia in the Kadazandusuns indicates that thalassemia screening, genetic counseling, and prenatal diagnosis should be included as part of their healthcare system. This preliminary paper serves as a baseline for further investigations into the health and genetic defects of the major indigenous population in Sabah, East Malaysia. © 2010 Jin-Ai Mary Anne Tan et al.

Item Type:Article
Uncontrolled Keywords:alpha thalassemia, article, beta thalassemia, genetic counseling, genetic screening, health care delivery, health care system, human, indigenous people, Malaysia, morbidity, prenatal diagnosis
Subjects:?? RC633-647.5 ??
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions:SCHOOL > School of Science and Technology
ID Code:2149
Deposited By:IR Admin
Deposited On:09 Mar 2011 18:31
Last Modified:18 Feb 2015 11:56

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