New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas

Takashi Kamada, and Phan, Chin Soon and Charles Santhanaraju Vairappan, (2019) New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas. Natural Product Research: Formerly Natural Product Letters, 33 (4). pp. 464-471. ISSN 1478-6419 (Print), 1478-6427 (Online)

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Abstract

Three new halogenated tricyclic sesquiterpenes, omphalaurediol (1), rhodolaurenones B (2) and C (3) were isolated together with nine known haloganated sesquiterpenes such as rhodolaurenone A (4), rhodolaureol (5), isorhodolaureol (6), (−)-laurencenone D (7), elatol (8), (+)-deschloroelatol (9), cartilagineol (10), (+)-laurencenone B (11) and 2-chloro-3-hydroxy-α-chamigren-9-one (12) from a population of Bornean red algae Laurencia majuscula. The structures of three new metabolites were determined based on their spectroscopic data (IR, 1D and 2D NMR, and MS). These compounds showed antibacterial activity against three human pathogenic bacteria (Escherichia coli, Salmonella typhi and Vibrio cholera).

Item Type: Article
Uncontrolled Keywords: Laurencia majuscula, halogenated tricyclic sesquiterpene, omphalane, rhodolaurane, antibacterial activity
Subjects: S Agriculture > SB Plant culture
S Agriculture > SH Aquaculture. Fisheries. Angling
Divisions: SCHOOL > Institute for Tropical Biology and Conservation
Depositing User: MDM SITI AZIZAH IDRIS
Date Deposited: 04 Jun 2020 23:31
Last Modified: 04 Jun 2020 23:31
URI: http://eprints.ums.edu.my/id/eprint/25481

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