Antioxidative and antibacterial activities of Pangium edule seed extracts

Yee , Chye Fook and Yuen , Sim Kheng (2009) Antioxidative and antibacterial activities of Pangium edule seed extracts. International Journal of Pharmacology, 5 (5). pp. 285-297. ISSN 1811-7775

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Official URL: http://dx.doi.org/10.3923/ijp.2009.285.297

Abstract

Phenolic and alkaloid extracts of Pangium edule Reinw (Flacourtiaceae) seed were investigated for their antioxidative activities using DPPH radical scavenging and β-carotene bleaching assays. The extracts were evaluated for antibacterial activity against Salmonella typhimurium and Listeria monocytogenes. The acetone extract with higher phenolic content (22.22±0.05 mg GAE g-1) showed the most potent antioxidative activity in both DPPH radical scavenging and β-carotene bleaching assays as compared to other extracts. The phenolic extract seems to have stronger inhibitory against L. monocytogenes than S. typhimurium. The free phenolic acid extract was found to have the highest Minimum Inhibition Concentration (MIC) among the seed extracts, indicates its weak antibacterial activity against both bacteria. Nevertheless, both tested pathogens were killed at the Minimum Bactericidal Concentration (MBC) of 30.3 and 55.5 mg mL-1, respectively, for the phenolic extracts. Significant correlation (p<0.05) was observed between the total phenolic content and its antioxidative activity (r = 0.878) as well as antibacterial (r = 0.840) activity suggesting that phenolics of the seed extract could be potential sources of natural antioxidant and antibacterial. © 2009 Asian Network for Scientific Information.

Item Type:Article
Uncontrolled Keywords:Alkaloids, Listeria monocytogenes, Minimum inhibition concentration, Natural antioxidant, Phenolics, Salmonella typhimurium
Subjects:?? SB354-402 ??
Divisions:SCHOOL > School of Food Science and Nutrition
ID Code:2549
Deposited By:IR Admin
Deposited On:24 Mar 2011 17:39
Last Modified:24 Feb 2015 10:40

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