Bioassay guided isolation of bio-active metabolites from several species of Malaysian Soft Coral

Jega Divan Sundramoorthy, (2005) Bioassay guided isolation of bio-active metabolites from several species of Malaysian Soft Coral. Universiti Malaysia Sabah. (Unpublished)

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Abstract

The research was done on four species of soft corals collected at Tanjung Aru beach at Kota Kinabalu, Sabah. The species were identified as, 1) Sinularia. sp1 , 2) Sinularia.sp2, 3) Lobophyton. sp1 and 4) Sarcophyton. sp2. This soft corals possess bioactivity towards some laboratory bacteria strains. Bioactivity-guided fractionation of hexane extract from Sinularia. sp1 and Sarcophyton. sp2 resulted in isolation of 5 bioactive metabolites. The bioactive metabolites isolated from Sinuiaria. sp1 are (1) 9-Fatty Acid Methyl Esters (FAME) which are C6:0, C14:0, C16:0, C16:1, C18:ln9t, C18:ln9c, C17:0, C18:2n6t and C24:1 together with a (2) Sterol. Bioactive isolation of metabolites from Sarcophyton. sp2 resulted in isolation of 3 bioactive metabolites which are (3) Compound A, (4) Compound Band (5) Compound C. The Fatty Acid Methyl Esters and Sterol isolated were found to be active against the environmental bacteria strain Clostridium cellobioparum while Compound A, Compound B and Compound C were active towards the environmental bacteria strain Clostridium sordelli.

Item Type: Academic Exercise
Uncontrolled Keywords: soft coral, bioactivity, Fatty Acid Methyl Ester, Sterol, bacteria strain, Tanjung Aru beach, hexane extract
Subjects: S Agriculture > SH Aquaculture. Fisheries. Angling
Divisions: SCHOOL > School of Science and Technology
Depositing User: MDM SITI AZIZAH IDRIS
Date Deposited: 01 Apr 2014 07:30
Last Modified: 10 Oct 2017 08:54
URI: http://eprints.ums.edu.my/id/eprint/8039

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