Chemical profiling and isolation of bioactive metabolites of Gorgonians

Kishneth Palaniveloo, (2007) Chemical profiling and isolation of bioactive metabolites of Gorgonians. University Malaysia Sabah. (Unpublished)

[img]
Preview
Text
ae0000002245.pdf

Download (2MB) | Preview

Abstract

This project studies the bioactive properties of the Gorgonians, being carnivorous soft corals with specialised nerve cells. These organisms are intermediate between hard corals and soft corals as they contain a rigid skeleton and are classified under the phylum Cnidarians. Five samples of Gorgonians were studied (Ug#k#spl, UG#k#sp2, Ug#k#sp3, UG#k#sp5, Ug#k#sp6). Yield of crude for all 5 species displayed prominent bioactive properties by inhibiting the growth of environmental bacteria, leading to the isolation of compound 1 from the MeOH crude ofUg#k#sp6. As much as 0.847 g (0.37%) of MeOH crude and 0.936 g (0.41%) of Hexane crude was obtained from the species studied. Therefore, based on spectral data Compound 1 that was isolated from Ug#k#sp6 can be assigned as CgHlg06. This compound is active against Clostridium sordelli and Vibrio parahaemolyticus. Apart from this, suspected sterols were isolated from all 5 species and a pattern of similarity could be seen as they contained approximately the same Rf value based on Thin Layer Chromatography suggesting their use as biomarkers for species of Gorgonian. Studies on marine natural product shows the various defence of marine organisms towards the environment and isolation of these products can be put to beneficial use through recent advance in biotechnology.

Item Type: Academic Exercise
Uncontrolled Keywords: Gorgonian, carnivorous soft corals, rigid skeleton, Thin Layer Chromatography, marine organism, biotechnology
Subjects: S Agriculture > SH Aquaculture. Fisheries. Angling
T Technology > TD Environmental technology. Sanitary engineering
Divisions: SCHOOL > School of Science and Technology
Depositing User: MDM SITI AZIZAH IDRIS
Date Deposited: 19 May 2014 00:52
Last Modified: 13 Oct 2017 04:06
URI: http://eprints.ums.edu.my/id/eprint/9043

Actions (login required)

View Item View Item

Browse Repository
Collection
   Articles
   Book
   Speeches
   Thesis
   UMS News
Search
Quick Search

   Latest Repository

Link to other Malaysia University Institutional Repository

Malaysia University Institutional Repository