In vitro antioxidant potential of the essential oil and leaf extracts of Curcuma zedoaria Rosc.

Atiqur F M Mustafizur Rahman, and Monira Afroz, and Rafiquel Islam, and Kazi Didarul Islam, and Md Amzad Hossain, and Minkyun Na, (2014) In vitro antioxidant potential of the essential oil and leaf extracts of Curcuma zedoaria Rosc. Journal of Applied Pharmaceutical Science, 4 (2). pp. 107-111. ISSN 22313354

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Abstract

In this study, we examined the chemical composition of the essential oil and tested the antioxidant potential of the oil and leaf extracts of Curcuma zedoaria Rosc. The chemical compositions of the oil were analysed by GCMS. Twenty-four compounds representing 92.4% of the total oil was identified. The antioxidative potential was evaluated using two separate methods, inhibition of free radical 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and superoxide radicals scavenging activities assay. In the first case, the IC50 value of the oil was 14.8 ± 2.2. Among the extracts, the strongest activity was exhibited by the ethyl acetate extract (IC50 = 17.56 ± 1.6 μg/ml). In the superoxide radicals scavenging activities assay, ethyl acetate extract was superior to all other extracts (IC50 = 23.47 ± 1.2 μg/ml). Furthermore, the amount of total phenolic compounds was also determined as gallic acid equivalent. Thus, the natural products produced from C. zedoaria may be used in food and pharmaceutical industries.

Item Type: Article
Uncontrolled Keywords: Antioxidant activities, Curcuma zedoaria rosc, Essential oil,GC-MS,Total phenolics
Subjects: Q Science > QK Botany
Depositing User: MDM FAUZIAH MATSIN
Date Deposited: 18 Aug 2014 01:27
Last Modified: 12 Oct 2017 01:02
URI: http://eprints.ums.edu.my/id/eprint/9353

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