Effects of process variables on size of Chitosan-alginate capsules through extrusion-dripping method

Pogaku Ravindra, and Gim , Pao Lim and Hui , Yen Ong and Boon , Beng Lee and Muhammad Syarhabil Ahmad, and Harbant Singh, (2014) Effects of process variables on size of Chitosan-alginate capsules through extrusion-dripping method. Advanced Materials Research, 925 . pp. 8-12. ISSN 10226680

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Official URL: http://dx.doi.org/10.4028/www.scientific.net/AMR.9...

Abstract

The objective of this study was to investigate the effects of process variables on size of chitosan-alginate capsules produced through extrusion-dripping method. Chitosan-calcium chloride solution was extruded into sodium alginate to form chitosan-alginate capsules which have a defined inner core and membrane. The results showed that sodium alginate concentration, chitosan concentration, chitosan to calcium chloride concentration ratio, needle diameter, gelation time have significant effect on the diameter and membrane thickness of chitosan-alginate capsules. Under the tested condition, chitosan-alginate capsules with diameter in a range of 3.4 mm to 4.5 mm were produced. The membrane thickness of the capsules increased when the curing time increased from 5 min to 60 min. As the concentration of sodium alginate (0.3-0.9%w/v) and chitosan (0.4-1.0%w/v) increased, the diameter of the chitosan-alginate capsules increased. The diameter of chitosan-alginate capsules increased with decreasing the chitosan to calcium chloride concentration ratio (1:0.5-1:1.5).

Item Type:Article
Uncontrolled Keywords:Chitosan-alginate capsules; Extrusion dripping; Membrane thickness; Size
Subjects:T Technology > TA Engineering (General). Civil engineering (General)
ID Code:9623
Deposited By:IR Admin
Deposited On:01 Oct 2014 11:32
Last Modified:16 Feb 2015 12:35

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