Amount of tolerable lactose among lactase-phlorizin hydrolase (LPH) non-persister students in Universiti Malaysia Sabah

Teh, Joanne Wei Seen (2013) Amount of tolerable lactose among lactase-phlorizin hydrolase (LPH) non-persister students in Universiti Malaysia Sabah. Universiti Malaysia Sabah. (Unpublished)


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The objectives of the study were to determine the amount of lactose tolerable by subjects studying in UMS who have been identified as LPH non-persisters, the contribution of milk and dairy products towards their total calcium intake and their achievement of recommended servings of milk and dairy products. This study also aimed to compare the incidence of self-reported lactose intolerance with diagnosis as LPH non-persisters and its influence on their dairy consumption. A total of 40 randomly selected subjects completed the study protocol, comprising seven male and 33 female Malaysians with mean age of 21.88 ± 0.97 years. All were instructed to fast overnight. On the morning of the study, subjects consumed a lactose bolus within five minutes. Subjects were given increasing levels of lactose. Dosage started at 0g lactose. This was followed by a washout period of seven days. Then subjects were given 6g, 12g, 18g, 24g, 30g lactose. Dosage was increased by 6g every week until subjects had a breath hydrogen increment of >20 ppm two or three hours post-prandial or reported GI symptoms. Plasma glucose measurement was taken half hourly for as long as their hydrogen breath was being measured. Subjects completed a FFQ for habitual calcium intake. It was found that 12.5% subjects could not tolerate amount at 6g lactose, 37.5% at 12g lactose, 35.0% at 18g lactose, 10.0% at 249 lactose and 5.0% at 30g lactose. The percentages of calcium intake from dairy products among male and female subjects were 29.2% and 21.6% respectively. Although 80.0% of subjects perceived themselves as lactose tolerant prior to participating in this study, only 35.9% met the recommended daily serving of milk and dairy products. Since the prevalence of LPH non-persisters is high in Malaysia, Malaysians should consume dairy products up to their tolerable limit to benefit from the high calcium content. Sample size should be increased in ethnic groups that were under-represented in order to achieve a more representative result.

Item Type: Academic Exercise
Uncontrolled Keywords: lactose, lPH non-persisters, milk and dairy product, calcium intake
Subjects: T Technology > TX Home economics > Nutrition. Foods and food supply
Divisions: SCHOOL > School of Food Science and Nutrition
Date Deposited: 18 Mar 2015 04:27
Last Modified: 13 Oct 2017 06:29

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