Chin, Soon Phan and Yeaw, Shean Ng and Eun, A Kim and Kishneth Palaniveloo and Charles Santhanaraju Vairappan (2015) Capgermacrenes A and B, Bioactive Secondary Metabolites from a Bornean Soft Coral, Capnella sp. Marine Drugs, 13 (5). pp. 3103-3115. ISSN 1660-3397
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Capgermacrenes A and B, bioactive secondary metabolites from a Bornean soft coral, Capnella.pdf Download (675kB) | Preview |
Abstract
Two new bicyclogermacrenes, capgermacrenes A (1) and B (2), were isolated with two known compounds, palustrol (3) and litseagermacrane (4), from a population of Bornean soft coral Capnella sp. The structures of these metabolites were elucidated based on spectroscopic data. Compound 1 was found to inhibit the accumulation of the LPS-induced pro-inflammatory IL-1β and NO production by down-regulating the expression of iNOS protein in RAW 264.7 macrophages.
| Item Type: | Article |
|---|---|
| Keyword: | soft coral, Capnella sp., Nephtheidae, sesquiterpenoids, bicyclogermacrene |
| Subjects: | S Agriculture > SH Aquaculture. Fisheries. Angling |
| Department: | INSTITUTE > Institute for Tropical Biology and Conservation |
| Depositing User: | ADMIN ADMIN |
| Date Deposited: | 30 Oct 2015 12:26 |
| Last Modified: | 26 Jun 2020 11:14 |
| URI: | https://eprints.ums.edu.my/id/eprint/11956 |
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