Phan, Chin Soon and Ng, Shean Yeaw and Kim, Eun A and Jeon, You Jin and Kishneth Palaniveloo and Charles Santhanaraju Vairappan (2015) Capgermacrenes A and B, bioactive secondary metabolites from a Bornean soft coral, Capnella sp. Marine Drugs, 13 (5). pp. 3103-3115. ISSN 1660-3397
|
Text
Capgermacrenes_A_and_B.pdf Download (124kB) | Preview |
Abstract
Two new bicyclogermacrenes, capgermacrenes A (1) and B (2), were isolated with two known compounds, palustrol (3) and litseagermacrane (4), from a population of Bornean soft coral Capnella sp. The structures of these metabolites were elucidated based on spectroscopic data. Compound 1 was found to inhibit the accumulation of the LPS-induced pro-inflammatory IL-1 ß and NO production by down-regulating the expression of iNOS protein in RAW 264.7 macrophages."
| Item Type: | Article |
|---|---|
| Keyword: | soft coral; Capnella sp.; Nephtheidae; sesquiterpenoids; bicyclogermacrene |
| Subjects: | Q Science > Q Science (General) |
| Depositing User: | ADMIN ADMIN |
| Date Deposited: | 30 Oct 2015 12:16 |
| Last Modified: | 12 Oct 2017 12:25 |
| URI: | https://eprints.ums.edu.my/id/eprint/12009 |
Actions (login required)
 |
View Item |