Biosurfactants from marine Cyanobacteria collected in Malaysia, Sabah

Jakia Jerin Mehjabin and Liang Wei and Julie G. Petitbois and Taiki Umezawa and Fuyuhiko Matsuda and Charles S. Vairappan and Masaaki Morikawa and Tatsufumi Okino (2020) Biosurfactants from marine Cyanobacteria collected in Malaysia, Sabah. Journal of Natural Products. pp. 1-35.

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Abstract

ABSTRACT Chemical investigation of the organic extract from Moorea bouillonii, collected in Sabah, Malaysia, led to the isolation of three new chlorinated fatty acid amides, columbamides F (1), G (2), and H (3). The planar structures of 1–3 were established by a combination of mass spectrometric and NMR spectroscopic analyses. The absolute configuration of 1 was determined by Marfey’s analysis of its hydrolysate and chiral-phase HPLC analysis after conversion and esterification with Ohrui’s acid, (1S,2S)-2- (anthracene-2,3-dicarboximido) cyclohexanecarboxylic acid. Compound 1 showed biosurfactant activity by an oil displacement assay. Related known fatty acid amides columbamide D and serinolamide C exhibited biosurfactant activity with critical micelle concentrations of about 0.34 and 0.78 mM, respectively.

Item Type: Article
Keyword: Lipids,High-performance liquid chromatography,Assays,Absolute configuration,Toxicity
Subjects: S Agriculture > S Agriculture (General)
S Agriculture > SB Plant culture
Department: INSTITUTE > Institute for Tropical Biology and Conservation
Depositing User: SITI AZIZAH BINTI IDRIS -
Date Deposited: 02 Jun 2020 16:54
Last Modified: 28 Mar 2021 20:33
URI: https://eprints.ums.edu.my/id/eprint/25471

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