Phan, Chin Soon and Takashi Kamada and Charles S. Vairappan (2020) Two new epimers of C15-acetogenin, 4-epi-isolaurallene and 4-epi-itomanallene A as diastereomeric model. National Library Of Medicine, 34 (7).
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Two new epimers of C15-acetogenin, 4-epi-isolaurallene and 4-epi-itomanallene A as diastereomeric model.pdf Download (1MB) | Preview |
Abstract
Two new C15-acetogenins, 4-epi-isolaurallene (1) and 4-epi-itomanallene A (2) were isolated from a population of marine red alga Laurencia nangii Masuda from Carrington Reef. The structures of these compounds were determined intensively by NMR and HRESIMS data. Their configurations were elucidated by detailed comparison of chemical shifts, germinal protons splitting and NOE correlations with known and synthesized analogues. In addition, antibacterial activities of these compounds were evaluated. These compounds would serve as diastereomeric models for future reference. Since the isolaurallene, neolaurallene, 9-acetoxy-1,10,12-tribromo-4,7:6,13-bisepoxypentadeca-1,2-diene, itomanallene A and laurendecumallene A were isolated, compounds 1 and 2 were the sixth example of C15-acetogenin with dioxabicyclo[7.3.0]dodecene skeleton.
| Item Type: | Article |
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| Keyword: | Borneo , C15-acetogenin , Laurencia nangii , antibacterial , red alga |
| Subjects: | Q Science > QL Zoology |
| Department: | INSTITUTE > Institute for Tropical Biology and Conservation |
| Depositing User: | NORAINI LABUK - |
| Date Deposited: | 19 Jun 2020 08:14 |
| Last Modified: | 19 Jun 2020 08:14 |
| URI: | https://eprints.ums.edu.my/id/eprint/25534 |
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