Toshiyuki Hamada and Kazushi Kobayashi and Naomichi Arima and Fumito Tani and Charles Santhanaraju Vairappan and Satoaki Onitsuka and Hiroaki Okamura (2020) Two cytotoxic squalene-derived polyethers from the Japanese red alga Chondria armata. Natural Product Research.
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Abstract
The red alga Chondria armata is known to produce and contain a rich diversity of secondary metabolites, such as domoic acid-related alkaloids and triterpene polyethers. Our investigation on red alga C. armata from Kagoshima coast, Japan, resulted in the isolation of two new triterpene polyethers, bandokorols A (1) and B (2). The structures of these compounds were determined based on spectroscopic data such as infrared (FTIR), 1H-NMR, APT, 1H–1H-COSY, HSQC, HMBC, NOESY and FAB mass spectrometry (HRFABMS). The anticancer potentials of these compounds were tested against adult T-cell leukaemia (ATL), S1T cells and their IC50 values are reported here.
| Item Type: | Article |
|---|---|
| Keyword: | Chondria armata, Rhodomelaceae, red alga, cytotoxicity, triterpenoids, adult T-cell leukemia, S1T |
| Subjects: | Q Science > Q Science (General) |
| Department: | INSTITUTE > Institute for Tropical Biology and Conservation |
| Depositing User: | SITI AZIZAH BINTI IDRIS - |
| Date Deposited: | 21 Sep 2020 08:24 |
| Last Modified: | 21 Sep 2020 08:24 |
| URI: | https://eprints.ums.edu.my/id/eprint/25981 |
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