A new bioactive cembranoid sarcophytonolide V from Bornean soft coral genus Sarcophyton

Kazuki Tani and Takashi Kamada and Phan, Chin Soon and Charles S. Vairappan (2019) A new bioactive cembranoid sarcophytonolide V from Bornean soft coral genus Sarcophyton. Natural Product Communications. pp. 1-4.

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Abstract

A new cembranolide diterpene, sarcophytonolide V (1), along with 6 known compounds, isosarcophytonolide D (2), (4Z,8S*,9R*,12E,14E) -9-hydroxy-1- (prop-1-en-2-yl) -8,12- dimethyl- oxabicyclo[9.3.2]-hexadeca-4,12,14-trien-18-one (3), (7E,11E)-3,4-epoxy-7,11, 15- cembratriene (4), (1S*,3S*,4S*,7E,11E)-3,4-epoxy-13-oxo-7,11,15-cembratriene (5), (-) -eunicenone (6), and 2-[(E,E,E)-7′, 8′-epoxy-4′,8′,12′ -trimethylcyclotetradeca- 1′,3′,11′- trienyl] propan-2-ol (7) were isolated from the Bornean soft coral Sarcophyton sp. Their structures were elucidated based on spectroscopic data, such as nuclear magnetic resonance (NMR) and high resolution electron spray ionization mass spectroscopy (HRESIMS). These compounds were evaluated for their biological activity against marine pathogenic fungi.

Item Type: Article
Keyword: Sarcophyton, Alcyoniidae, soft coral, cembrane, diterpene, antifungal
Subjects: S Agriculture > SH Aquaculture. Fisheries. Angling
Department: INSTITUTE > Institute for Tropical Biology and Conservation
Depositing User: SITI AZIZAH BINTI IDRIS -
Date Deposited: 02 Jun 2020 16:56
Last Modified: 02 Jun 2020 16:56
URI: https://eprints.ums.edu.my/id/eprint/25476

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