The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum

Kazuki Tani and Charles S. Vairappan (2022) The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum. Journal Of Tropical Biology And Conservation, 19. pp. 67-76. ISSN 1823-3902

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Abstract

The structure types and bioactivities of secondary metabolites derived from Litophyton arboreum, distributed in Sepanggar Bay, Sabah, Malaysia, were investigated as additional tools for establishing their species identification. As a result, a total of two secondary metabolites (alismol (1) and 10α-methoxy-4β-hydroxy guaian-6-ene (2)) were isolated from Bornean soft coral L. arboreum. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds 1 and 2 were determined. In addition, the compound 2 showed highest antifungal activity against Haliphthoros milfordensis. As a result of comparison with previous literature, significant variations were observed in relation to structure types of secondary metabolites and bioactivities. Information from this study gives additional evidence of chemotaxonomic significance and baseline data for effective selection of suitable lead pharmaceuticals.

Item Type: Article
Keyword: Soft coral, Litophyton arboreum, Sesquiterpene, Chemotaxonomy, Antifungal activity
Subjects: Q Science > QK Botany > QK1-989 Botany > QK710-899 Plant physiology
Department: INSTITUTE > Institute for Tropical Biology and Conservation
Depositing User: DG MASNIAH AHMAD -
Date Deposited: 15 May 2024 11:29
Last Modified: 15 May 2024 11:29
URI: https://eprints.ums.edu.my/id/eprint/38677

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