Three new cembranoids from the Bornean soft coral Nephthea sp.

Charles Santhanaraju Vairappan, and Takashi Kamada, and Takashiro Ishii, (2016) Three new cembranoids from the Bornean soft coral Nephthea sp. Journal of Asian Natural Products Research, 18 (5). pp. 415-422. ISSN 1028-6020 (Print), 1477-2213 (Online)

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Official URL: http://dx.doi.org/10.1080/10286020.2016.1145670

Abstract

Three new cembranoid diterpenes, 10-hydroxy-nephthenol acetate (1), 7,8-epoxy-10-hydroxy-nephthenol acetate (2), and 6-acetoxy-7,8-epoxy-10-hydroxy-nephthenol acetate (3), along with a known compound, 6-acetoxy-7,8-epoxy-nephthenol acetate (4), were isolated from the Bornean soft coral Nephthea sp. Antibacterial and anticancer activities were exhibited by compounds 1 and 2 against Staphylococcus aureus (ATCC 6538)/Escherichia coli (ATCC 13311) and Hela/MCF-7, respectively.

Item Type:Article
Uncontrolled Keywords:Cembranoid, Nephthea sp., Nephtheidae, Bornean soft coral
Subjects:Q Science > QH Natural history > QH301 Biology
Divisions:SCHOOL > Institute for Tropical Biology and Conservation
ID Code:13798
Deposited By:IR Admin
Deposited On:09 Aug 2016 12:57
Last Modified:09 Aug 2016 12:57

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