Analytical determination of nicotine in tobacco leaves by gas chromatography-mass spectrometry

Hossain, Amzad and Syed M. Salehuddin, (2010) Analytical determination of nicotine in tobacco leaves by gas chromatography-mass spectrometry. Arabian Journal of Chemistry . (In Press)

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Official URL: http://dx.doi.org/10.1016/j.arabjc.2010.10.006

Abstract

A preliminary investigation using gas chromatography–mass spectrometry (GC–MS) to analyze the nicotine contained in tobacco leaves was carried out. Nicotine in commercially available cigarettes and tobacco leaves was extracted with methanol and determined by GC–MS. The detection limit was at the ppm level for nonselective monitoring and the nanogram level for nicotine selective detection. This system provided a simple analytical method for the analysis of nicotine in tobacco leaves. Compared to currently utilized methods, the GC–MS provided advantages of high sensitivity, nicotine specific detection and lower instrumentation cost.

Item Type:Article
Uncontrolled Keywords:Tobacco leaves, Quantification, Nicotine, Gas chromatography–mass spectrometry
Subjects:Q Science > QP Physiology
Divisions:SCHOOL > Biotechnology Research Institute (BRI)
ID Code:1903
Deposited By:IR Admin
Deposited On:24 Feb 2011 17:41
Last Modified:18 Feb 2015 10:48

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