Md. Feroz Hossain, (2011) Semen quality in pesticide spraying Sabah farmers: A cross-sectional study. Masters thesis, Universiti Malaysia Sabah.
Epidemiological studies have indicated a decline in semen quality to almost half over the last five decades among healthy men all over the world. Pesticide exposure has been proposed as one of the major causes for such a decline. Organophosphate pesticide is the most commonly used insecticide in the world. Herbicide such as "Paraquat" is highly toxic to human and has serious and irreversible delayed effects if absorbed. The pesticides are routinely used by the farmers in Sabah, Malaysia. The aim of the present study was to assess the effects of pesticides use on semen quality among farmers in Telupid, Kundasang and Papar district of Sabah, Malaysia. Cross - sectional study was conducted among male farmers from three different places in Sabah, Malaysia. A total of 152 volunteers participated in this study of which 62 volunteers were exposed to pesticides to varying extents. Remaining 90 volunteers were not exposed to pesticides. A questionnaire was designed to record a history of pesticides exposure and other potential risk factors among farmers. Population profile, exposure patterns and other potential risk factors were obtained. All semen samples were collected by masturbation into a sterile wide-mouth glass container in a laboratory. Sexual abstinence of 2-3 days was advised to the volunteers. The samples were kept in an incubator at 36-37⁰ c until liquefaction and subsequently examined. All semen samples were examined and analysed based on WHO (1992) guidelines. Volume, pH, sperm concentration, motility, morphology, white blood cell count were examined and recorded. Frequencies, descriptive data, group statistics, independent sample t test, chi-square test were performed. It showed abnormal semen parameters were associated with pesticide exposure. The mean values of volume, pH, sperm concentration, sperm motility, sperm morphology were significantly less and white blood cell count was significantly high in the exposed group when compared with the non-exposed, with p values of less than 0.05. Those who were exposed to pesticides had risk of having abnormal semen parameters in compare with the non-exposed group, with p values of less than 0.05. And there were no significant difference observed in relation to potential risk factors. The result showed the abnormal semen parameters were associated with pesticide exposure and there was increase in the risk of impaired semen quality among people who had exposed to pesticides.
|Item Type:||Thesis (Masters)|
|Uncontrolled Keywords:||semen quality, Organophosphate pesticide, farmer, Cross - sectional study|
|Subjects:||R Medicine > R Medicine (General)|
|Divisions:||SCHOOL > School of Medicine|
|Deposited By:||IR Admin|
|Deposited On:||09 Jul 2014 09:38|
|Last Modified:||09 Jul 2014 09:38|
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