Phytochemical and biological studies on sweet potato(Ipomoea Batatas)

Lai, Chan Wei (2007) Phytochemical and biological studies on sweet potato(Ipomoea Batatas). Universiti Malaysia Sabah. (Unpublished)


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Sweet potato has received a broad attention because it is an important resource of food and there is an abundance of pharmacologically active ingredients in it. Three genotypes (storage roots and leaves) of sweet potato commercially available in Sabah (orange and purple fleshed) were studied for its phytochemical contents, antioxidation, antimicrobial and anti-kinase (MAPK) properties. Methanol crude extracts were obtained which were further partitioned into petroleum ether, chloroform and butanol extracts using solvent-solvent extractions. Phytochemical screenings demonstrated that the petroleum ether and chloroform extracts of all the genotypes contained saponins, tannins and anthraquinones whereas the butanol extract contained more classes of compounds (saponins, tannins, flavonoids and anthraquinones). The petroleum ether extract of storage roots (purple fleshed, Tambunan) showed a very potent antioxidation activity with relative anti oxidation value of 1.025 (compared to fullness BHT, a synthetic antioxidant) as evaluated using the ferric thiocyanate (FTC) method. Petroleum ether extracts showed moderate to strong antioxidation activities. All the extracts demonstrated moderate antimicrobial activities against S. aureus (S 277) and B. cereus (B 43/04B) as evaluated a disc diffusion method. Relatively, the butanol extract was the most potent antimicrobial agent among all the extracts. However, no inhibition against E. coli (E 911026) was observed. It was interesting to found out that all the butanol extracts of the storage roots showed very potent MAPK kinase inhibition as evaluated using a yeast screening system (yeast growing zone was 17 mm). However, inhibition of GSK-3B was only detected in the petroleum ether extract of the leaves with 15 mm inhibition zone. Hence, sweet potato can be used as an easy accessible source of natural antioxidants, as a food supplement, or in the pharmaceutical and medical industries.

Item Type: Academic Exercise
Uncontrolled Keywords: Sweet potato, natural antioxidant, food supplement, pharmaceutical, medical industry
Subjects: Q Science > QK Botany
Divisions: SCHOOL > School of Science and Technology
Date Deposited: 21 Nov 2013 14:33
Last Modified: 11 Oct 2017 10:57

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