What proteins are involved in learning and memory?

Permah @ Perumal Ramasamy and Tan, I. (2007) What proteins are involved in learning and memory? IUBMB Life, 59 (7). pp. 465-468. ISSN 1521-6543


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Learning is the acquisition of new knowledge while memory is retention of the new knowledge. Recently acquired knowledge is stored in short-term memory (STM). If that knowledge is reinforced through repetition, it is consolidated into long-term memory (LTM). The latter is modified over time with acquisition of new information by either further reinforcement of the synaptic circuits or through nonuse, by pruning of such circuits. This accounts for neuronal plasticity. The process of consolidation of learning and memory is very crucial to the survival of organisms. There is great interest in unveiling and in understanding of the underlying mechanism of this process. To achieve this, a popular strategy is to use the simpler and more easily manipulated nervous systems of invertebrates to generate information that can be applied on the more complex nervous systems of vertebrates.

Item Type: Article
Keyword: Growth hormone, guanine nucleotide binding protein, hypophysis adenylate cyclase activating polypeptide Caenorhabditis elegans, controlled study, Drosophila melanogaster, footshock, learning, long term memory, memory, memory consolidation, nonhuman, protein phosphorylation, review, short term memory, smelling Humans, Learning, Memory, Mice, Mice, Inbred C57BL, Proteins, Rats Medline is the source for the MeSH terms of this document.
Subjects: T Technology > TP Chemical technology > TP1-1185 Chemical technology > TP248.13-248.65 Biotechnology
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Department: SCHOOL > School of Medicine
Depositing User: ADMIN ADMIN
Date Deposited: 29 Apr 2011 17:11
Last Modified: 16 Oct 2017 13:13
URI: https://eprints.ums.edu.my/id/eprint/2899

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