A mini review on emerging targets and approaches for the synthesis of anti-viral compounds- in perspective to covid-19

Maheswara Rao Gokada and Pasupuleti Visweswara Rao and Hari Babu Bollikolla (2021) A mini review on emerging targets and approaches for the synthesis of anti-viral compounds- in perspective to covid-19. Mini-Reviews in Medicinal Chemistry, 21. pp. 1173-1181. ISSN 1875-5607

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A mini review on emerging targets and approaches for the synthesis of anti-viral compounds- in perspective to covid-19 ABSTRACT.pdf

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Abstract

The novel Coronavirus disease (COVID-19) is an epidemic disease that appeared at the end of the year 2019 with a sudden increase in number and came to be considered as a pandemic disease caused by a viral infection which has threatened most countries for an emergency search for new anti-SARS-COV drugs /vaccines. At present, the number of clinical trials is ongoing worldwide on different drugs i.e. Hydroxychloroquine, Remedisvir, Favipiravir that utilize various mechanisms of action. A few countries are currently processing clinical trials, which may result in a positive outcome. Favipiravir (FPV) represents one of the feasible treatment options for COVID-19, if the result of the trials turns out positive. Favipiravir will be one of the developed possibly authoritative drugs to warrant benefits to mankind with large-scale production to meet the demands of the current pandemic Covid-19 outbreak and future epidemic outbreaks. In this review, the authors tried to explore key molecules, which will be supportive for devising COVID-19 research.

Item Type: Article
Keyword: Coronavirus , Hydroxychloroquine , Remedisvir , Favipiravir , Mechanism of action , Covid-19
Subjects: R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA421-790.95 Public health. Hygiene. Preventive medicine > RA643-645 Disease (Communicable and noninfectious) and public health
Department: FACULTY > Faculty of Medicine and Health Sciences
Depositing User: SAFRUDIN BIN DARUN -
Date Deposited: 20 Sep 2021 12:14
Last Modified: 20 Sep 2021 12:14
URI: https://eprints.ums.edu.my/id/eprint/30325

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