Occlusive retinal vasculitis in an immunocompetent woman: rare presentation of ocular melioidosis

Huwaina Abdul Satar and Muhammad Ikmal Mohamad Kamil and Rosiah Muda and Liza Sharmini Ahmad Tajudin (2021) Occlusive retinal vasculitis in an immunocompetent woman: rare presentation of ocular melioidosis. Malaysian Journal of Ophthalmology (MyJO), 3. pp. 175-182. ISSN 2665-9557 (P-ISSN) , 2665-9565 (E-ISSN)

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Burkholderia pseudomallei is a known great mimicker responsible for melioidosis. Melioidosis presents with a wide spectrum of clinical presentations in various organs including the eye. Ocular involvement in melioidosis is unusual, with eyelid and orbital infection as the commonest presentation. We describe a 41-year-old, healthy woman who complained of reduced vision in her left eye. On examination, vision in the left eye was 6/9. There was evidence of occlusive retinal vasculitis on fundoscopy examination. Fundus fluorescein angiogram showed extensive capillary fallout. Diagnosis was established by a rise in the serum antibody titre for the bacterium and further supported by clinical improvement of vision after completion of treatment antibiotics: third-generation cephalosporin and combination of amoxicillin and clavulanic acid. Sectoral panretinal photocoagulation at the capillary fallout area successfully arrested the sequelae of retinal ischaemia. Occlusive retinal vasculitis is a rare presentation of melioidosis. Early prompt diagnosis of ocular melioidosis in an immunocompetent individual helps prevent visual-related morbidity. The ability of this bacteria to cause recurrent infection in an endemic area should not be under-estimated.

Item Type: Article
Keyword: Burkholderia pseudomallei , Immunocompetence , Melioidosis , Occlusive retinal vasculitis
Subjects: R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC109-216 Infectious and parasitic diseases
Department: FACULTY > Faculty of Medicine and Health Sciences
Date Deposited: 29 Mar 2022 11:58
Last Modified: 29 Mar 2022 11:58
URI: https://eprints.ums.edu.my/id/eprint/32049

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