Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy

Rosli Ismail and Mohd Firdaus Che Ani and Salahuddin Baharom and Nornazirah Azizan and Andee Dzulkarnaen Zakaria and Mohd Firdaus Mohd Hayati (2022) Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy. Gazi Medical Journal, 33 (4). pp. 423-425. ISSN 2147-2092

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Goblet cell carcinoid (GCC) is an enigmatic and rare tumour involving the appendix almost exclusively. It is a rare, aggressive subtype of appendiceal tumours with neuroendocrine features, and controversy exists with regards to therapeutic strategy. We herein highlight a 56-year-old lady with GCC whom she presented initially with a typical presentation of acute appendicitis. The histologic hallmark of this entity is the presence of clusters of goblet cells in the lamina propria or submucosa stain for various neuroendocrine markers, though the intensity is often patchy. GCC of the appendix is rare and challenging. In advanced form, it can present with carcinoid symptoms but occasionally mimics classical presentations of acute appendicitis. A tumour measuring less than 1 cm and located at the tip of the appendix is sufficient for a simple appendicectomy which warrants a promising prognosis.

Item Type: Article
Keyword: Appendectomy , Appendicitis , Goblet cell carcinoid
Subjects: R Medicine > RD Surgery > RD1-811 Surgery > RD520-599.5 Surgery by region, system, or organ
Department: FACULTY > Faculty of Medicine and Health Sciences
Depositing User: SAFRUDIN BIN DARUN -
Date Deposited: 29 Sep 2022 11:16
Last Modified: 29 Sep 2022 11:16

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