Approaches to phyllodes tumour of the breast: a review article

Mohd Firdaus Mohd Hayati and Ho, Hui Lian and Nornazirah Azizan and Aishath Azna Ali and Zainal Adwin Zainal Abidin and Muhamad Aznan Suhaili (2017) Approaches to phyllodes tumour of the breast: a review article. International Surgery Journal, 4. pp. 841-845. ISSN 2349-3305 (P-ISSN) , 2349-2902 (E-ISSN)

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Phyllodes tumours are rare entities of fibroepithelial diseases. The exact pathogenesis and their relationship with fibroadenomas are oblivious. Women aged between 35 to 55 years are commonly affected, even younger in Asian population. Triple assessment should be applied as a guide to management in any breast pathology. Clinical appearances are typically diagnostic for phyllodes tumours. Even though sometimes inconclusive, mammography and ultrasonography are the main imaging modalities. Although the role of cytology is debatable, presence of both epithelial and stromal elements supports the diagnosis especially in malignant type. Core biopsy is rather favored in view of higher accuracy for the diagnosis. Accurate preoperative assessment and histologic diagnosis allow correct surgical intervention and subsequent avoidance of reoperation. Surgical management can be either wide excision with more than 1 cm margins or mastectomy without axillary surgery. Local recurrence has been associated with inadequate excision of the pseudopod. Adjuvant radiotherapy is recommended for positive surgical margin and for local control of borderline and malignant phyllodes tumors. The role of chemotherapy and endocrine therapy has not been fully studied.

Item Type: Article
Keyword: Cystosarcoma phyllodes , Fibroadenoma , Phyllodes tumours , Pseudopod , Triple assessment
Subjects: R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
Department: FACULTY > Faculty of Medicine and Health Sciences
Depositing User: SAFRUDIN BIN DARUN -
Date Deposited: 11 Oct 2022 12:47
Last Modified: 11 Oct 2022 12:47

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