Chian Ho and Lee, Ping Chin (2022) COVID-19 Treatment—Current Status, Advances, and Gap. Pathogens, 11. pp. 1-15. ISSN 2076-0817
![]() |
Text
Abstract.pdf Download (42kB) |
![]() |
Text
Full text.pdf Restricted to Registered users only Download (318kB) | Request a copy |
Abstract
COVID-19, which emerged in December 2019, was declared a global pandemic by the World Health Organization (WHO) in March 2020. The disease was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has caused millions of deaths worldwide and caused social and economic disruption. While clinical trials on therapeutic drugs are going on in an Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) public–private partnership collaboration, current therapeutic approaches and options to counter COVID-19 remain few. Therapeutic drugs include the FDA-approved antiviral drugs, Remdesivir, and an immune modulator, Baricitinib. Hence, therapeutic approaches and alternatives for COVID-19 treatment need to be broadened. This paper discusses efforts in approaches to find treatment for COVID-19, such as inhibiting viral entry and disrupting the virus life cycle, and highlights the gap that needs to be filled in these approaches.
Item Type: | Article |
---|---|
Keyword: | COVID-19 , Peptides , Virus life cycle , FDA-approved drugs , Drug development |
Subjects: | R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA421-790.95 Public health. Hygiene. Preventive medicine > RA643-645 Disease (Communicable and noninfectious) and public health R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA421-790.95 Public health. Hygiene. Preventive medicine > RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection |
Department: | INSTITUTE > Biotechnology Research Institute (BRI) |
Depositing User: | SITI AZIZAH BINTI IDRIS - |
Date Deposited: | 23 Mar 2023 10:12 |
Last Modified: | 23 Mar 2023 10:12 |
URI: | https://eprints.ums.edu.my/id/eprint/35232 |
Actions (login required)
![]() |
View Item |