Stereospecific/stereoselective nickel catalyzed reductive cross-coupling: An efficient tool for the synthesis of biological active targeted molecules

Uzma Afzal and Muhammad Bilal and Muhammad Zubair and Nasir Rasool and Syed Adnan Ali Shah and Zainul Amiruddin Zakaria (2023) Stereospecific/stereoselective nickel catalyzed reductive cross-coupling: An efficient tool for the synthesis of biological active targeted molecules. Journal of Saudi Chemical Society, 27. pp. 1-45. ISSN 1319-6103

	Text ABSTRACT.pdf Download (36kB)
	Text FULL TEXT.pdf Restricted to Registered users only Download (3MB) \| Request a copy

URL: https://www.sciencedirect.com/science/article/pii/...

Abstract

Reductive cross-electrophile transformations have recently been made into a robust and long-lasting synthetic technique for the production of specific CAC bonds. The use of inexpensive and plentiful electrophiles eliminates the need for pre-formation and handling of organometallics. In stereospecific reductive cross-coupling, nickel is one of the most cost-effective and flexible transition metals. This paper examines current developments in nickel catalyzed reductive cross coupling reactions and their potential application for the synthesis of biologically active molecules over the previous nine years.

Item Type:	Article
Keyword:	Reductive, Cross-coupling, Electrophile, Bioactive
Subjects:	Q Science > QD Chemistry > QD1-999 Chemistry > QD450-801 Physical and theoretical chemistry R Medicine > RC Internal medicine > RC31-1245 Internal medicine
Department:	FACULTY > Faculty of Medicine and Health Sciences
Depositing User:	SITI AZIZAH BINTI IDRIS -
Date Deposited:	02 May 2024 16:47
Last Modified:	02 May 2024 16:47
URI:	https://eprints.ums.edu.my/id/eprint/38603

Actions (login required)

View Item