Colorimetric determination of iron in vitamin supplements

Bong, Lee Kim (2007) Colorimetric determination of iron in vitamin supplements. Universiti Malaysia Sabah. (Unpublished)


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A study was done to determine the concentration of iron (Fe) from five different brands of vitamin supplement, namely Seven Sea (S 1), Revicon (S2), Obimin (S3), Pharmaton (S4) and Vita-Kaps-R (S5). All samples were obtained from the local pharmacy. The sample chosen was first powdered and diluted with HCl. Then, the solution was filtered and being prepared for Fe analysis by adding o-phenanthroline as a color forming reagent and NH₂0HCI as a reducing agent. Subsequent analysis was carried out by using UV -Visible Spectrophotometer based on absorbance at 508 run. The relationship between absorbance and concentration was in accordance to the Beer-Lambert law for the Fe concentration range 0-1 mg/L while higher concentrations resulted a negative deviation from the Beer's law. The concentration of each sample was calculated according to the linear equation of the calibration curve made earlier. The Fe content per tablet for each vitamin sample was 11.32 ± 1.47,6.41 ± 0.33, 59.1 ± 22.20, 7.69 ± 0.64 and 6.75 ± 1.12 mg/tablet respectively. The proposed method was more applicable for the determination of Fe in vitamin supplement with low Fe contents.

Item Type: Academic Exercise
Keyword: Vitamin supplement, Pharmacy, Local Pharmacy, Colorimetric
Subjects: R Medicine > RS Pharmacy and materia medica > RS153-441 Materia medica > RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Department: SCHOOL > School of Science and Technology
Depositing User: ADMIN ADMIN
Date Deposited: 10 Sep 2012 16:21
Last Modified: 10 Oct 2017 17:40

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