Essential oil composition, cytotoxic and antibacterial activities of five Elingera species from Borneo

Charles Santhanaraju Vairappan and Nagappan, Thilahgavani and Palaniveloo, Krishneth (2012) Essential oil composition, cytotoxic and antibacterial activities of five Elingera species from Borneo. Natural Product Communications, 7 (2). pp. 239-242. ISSN 1555-9475


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Essential oils obtained by hydrodistillation from the rhizomes of Etlingera pyramidosphaera (K. Schum.) R. M. Sm, E. megalocheilos (Griff.) A.D. Poulsen, comb. nov., E. coccinea (Blume) S. Sakai & Nagam, E. elatior (Jack) R. M. Sm, and E. brevilabrum (Valeton) R. M. Sm were analyzed by GCMS. The highest oil yield was obtained from E. pyramidosphaera (0.45%), followed by E. elatior (0.38%), E. coccinea (0.30%), E. brevilabrum (0.28%) and E. megalocheilos (0.25%). The major constituents of the essential oils were oxygenated monoterpenes, followed by sesquiterpenes, oxygenated sesquiterpenes, oxygenated diterpenes and diterpenes. The essential oils from E. pyramidosphaera and E. brevilabrum exhibited the best cytotoxicity against MCF 7 (LC 50: 7.5±0.5 mg mL ¯¹) and HL 60 (LC 50: 5.0 mg mL ¯¹), respectively. Strong inhibition was also observed for the essential oils of E. coccinea and E. megalocheilos against Staphylococcus aureus (MIC: 8.0±0.5 mg mL ¯¹, and 5.0.,b0.5 mg mL ¯¹) and Streptococcus pyrogenes (MIC: 6.0±0.5 mg mL ¯¹ and 8.0±0.5 mg mL ¯¹ ).

Item Type: Article
Keyword: Antibacterial activity, Borneo, Cytotoxic, Essential oil, Etlingera, Antiinfective agent, Antineoplastic agent, Diterpene, Essential oil, Etlingera brevilabrum extract, Etlingera coccinea extract, Etlingera elatior extract, Etlingera megalocheilos extract, Etlingera pyramidosphaera extract, Herbaceous agent, Plant extract, Sesquiterpene, sesquiterpene derivative, Terpene derivative, Unclassified drug, Antibacterial activity, Article, Cell strain HL 60, Cell strain MCF 7, Chemical composition, Drug cytotoxicity, drug isolation, Etlingera brevilabrum, Etlingera coccinea, Etlingera elatior, Etlingera megalocheilos, Etlingera pyramidosphaera, HeLa cell, Human, Human cell, IC 50, leukemia P 388, Mass fragmentography, Minimum inhibitory concentration, Nonhuman, Salmonella enteritidis, Staphylococcus, Staphylococcus aureus, Streptococcus pyogenes, Zingiberaceae
Subjects: Q Science > QD Chemistry > QD1-999 Chemistry > QD241-441 Organic chemistry
Q Science > QK Botany
Department: INSTITUTE > Institute for Tropical Biology and Conservation
Depositing User: ADMIN ADMIN
Date Deposited: 07 Dec 2012 18:01
Last Modified: 21 Jan 2021 12:50

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