Potential of antimicrobial activity of Ganoderma applanatum extract

Lim, Chiew Chin (2005) Potential of antimicrobial activity of Ganoderma applanatum extract. Universiti Malaysia Sabah. (Unpublished)


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The potential of Ganoderma applanatum as an agent antimicrobial was studied. The objective of this research was to determine the effectiveness of crude extract of the macrofungi in controlling the growth of pathogenic microbes. The factors like concentration, volume, and storage temperature and incubation period of the extract were investigated. The extracts were tested for their antimicrobial activity against several Gram-positive and Gram-negative bacteria and against one yeast species using disc diffusion method. Antibacterial activity was demonstrated especially against Grampositive bacteria including Staphylococcus aureus and Bacillus cereus. Concentration, volume, temperature and incubation period of the extract can affect the size of the inhibition zone against test organisms. High concentration of G. applanatum extract such as 500mg/ml was found to be capable of stopping the germination of the Candida albicans spores and decreased the germ-tube length. The result showed that the extract was stable against storage temperature but the length of incubation period of the extract has slightly decreased the effectiveness of the extract. Based on the current findings, it can be concluded that this fungus has antimicrobial activity, which is as potent as standard antimicrobial drugs against certain microorganisms.

Item Type: Academic Exercise
Keyword: Ganoderma applanatum, antimicrobial, crude extract, pathogenic microbe, length of incubation
Subjects: Q Science > QH Natural history > QH301-705.5 Biology (General)
Department: SCHOOL > School of Science and Technology
Date Deposited: 08 Jan 2014 10:53
Last Modified: 10 Oct 2017 15:58
URI: https://eprints.ums.edu.my/id/eprint/7968

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