Three new cembranoids from the Bornean soft coral Nephthea sp.

Charles Santhanaraju Vairappan and Takashi Kamada and Takashiro Ishii (2016) Three new cembranoids from the Bornean soft coral Nephthea sp. Journal of Asian Natural Products Research, 18 (5). pp. 415-422. ISSN 1028-6020 (Print), 1477-2213 (Online)

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Abstract

Three new cembranoid diterpenes, 10-hydroxy-nephthenol acetate (1), 7,8-epoxy-10-hydroxy-nephthenol acetate (2), and 6-acetoxy-7,8-epoxy-10-hydroxy-nephthenol acetate (3), along with a known compound, 6-acetoxy-7,8-epoxy-nephthenol acetate (4), were isolated from the Bornean soft coral Nephthea sp. Antibacterial and anticancer activities were exhibited by compounds 1 and 2 against Staphylococcus aureus (ATCC 6538)/Escherichia coli (ATCC 13311) and Hela/MCF-7, respectively.

Item Type: Article
Keyword: Cembranoid, Nephthea sp., Nephtheidae, Bornean soft coral
Subjects: Q Science > QH Natural history > QH301-705.5 Biology (General)
Department: INSTITUTE > Institute for Tropical Biology and Conservation
Depositing User: ADMIN ADMIN
Date Deposited: 09 Aug 2016 12:57
Last Modified: 16 Oct 2017 11:16
URI: https://eprints.ums.edu.my/id/eprint/13798

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