Mariani Rajin and A H Kamaruddin (2016) Effect of temperature on Candida antartica lipase B activity in the kinetic resolution of acebutolol. In: International Conference on Chemical Engineering and Bioprocess Engineering, 25-26 October 2016, Jeddah, Saudi Arabia.
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Abstract
Thermodynamic studies of free Candida antartica lipase B in kinetic resolution of acebutolol have been carried out to characterize the temperature effects towards enzyme stability and activity. A decreased in reaction rate was observed in temperature above 40oC. Thermodynamic studies on lipase deactivation exhibited a first-order kinetic pattern. The activation and deactivation energies were 39.63 kJ/mol and 54.90 kJ/mol, respectively. The enthalpy and entropy of the lipase deactivation were found to be 52.12 kJ/mol and -0.18 kJ/mol, respectively.
| Item Type: | Conference or Workshop Item (UNSPECIFIED) |
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| Keyword: | Thermodynamic, Candida antartica, kinetic resolution, acebutolol |
| Subjects: | Q Science > QC Physics |
| Department: | FACULTY > Faculty of Engineering |
| Depositing User: | Munira M |
| Date Deposited: | 02 Feb 2017 13:47 |
| Last Modified: | 12 Oct 2017 10:35 |
| URI: | https://eprints.ums.edu.my/id/eprint/15486 |
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