Toh, Denise Yew Leng (2006) Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef. Universiti Malaysia Sabah. (Unpublished)
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Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef..pdf Download (469kB) | Preview |
Abstract
This study was carried out on 5 Laurencia species. They are Laurencia snackeyi, Laurencia nangii, Laurencia sp., Laurencia papilose, and Laurencia cribb. Five halogenated secondary metabolites were isolated from L. snackeyi. The halogenated secondary metabolites are (2Z., 6S·, 9R·)-chamigr-2, 5(I4)-dien-8-one (80), Palisadin B (76), 5-acetoxypalisadin B (7), Aplysistatin (6), and 5f3-hydroxypalisadin B (81). The halogenated secondary metabolites were then tested against marine environmental bacteria, human pathogenic bacteria and yeast. (2Z., 6S·, 9R·)chamigr- 2, 5(l4)-dien-8-one (80) and Palisadin B (76) did not show any positive activity against aU of them 5-acetoxypalisadin B (7) and Aplysistatin (6) showed positive activity against 5 marine environmental bacteria which were Clostridium cellobioparum, Clostridium sordelli, Clostridium novyi, Vibrio arginolyticus and Vibrio parahaemolyticus. 5f3-hydroxypalisadin B (81) showed positive activity against 2 marine environmental bacteria which were Clostridium sordelli and Vibrio parahaemolyticus, 2 human pathogenic bacteria Vibrio chlolera and E. coli, and 2 different strains of Candida albicans yeast.
| Item Type: | Academic Exercise |
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| Keyword: | Laurencia species , marine environmental bacteria , human pathogenic bacteria |
| Subjects: | Q Science > QH Natural history |
| Department: | SCHOOL > School of Science and Technology |
| Depositing User: | NORAINI LABUK - |
| Date Deposited: | 04 Jun 2018 08:18 |
| Last Modified: | 04 Jun 2018 08:18 |
| URI: | https://eprints.ums.edu.my/id/eprint/20131 |
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