Aznida Mohamad Zaki and Muhammad Aklil Abd Rahim and Zuraidah Zaidun and Abdul Rahman Ramdzan and Zaleha Md Isa (2020) Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis. Middle East Journal of Cancer, 11 (1). pp. 1-11.
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Abstract
Background: A slight increase in the childhood cancer trend has been observed for the past few decades. Non-ionizing radiation is one of the environmental factors linked to childhood cancers. This review is conducted to assess the association between non-ionizing radiation and childhood cancer based on all original studies to date. Methods: A systematic search was conducted on the titles and abstracts pertaining to non-ionizing radiation and childhood cancers using the PubMed, Scopus, SAGE and ScienceDirect databases from inception up to November 2018. Quality of each article was appraised using the Newcastle-Ottawa Scale, meta-analysis was performed with Review Manager, and fixed effects were used to estimate the pooled OR of the selected studies. Results: A total of 15 articles met all the selection criteria. Twelve articles were included in the meta-analysis. Pooled risk estimates of the 12 studies, obtained via fixed effects model, showed that children exposed to 0.2 µT or more of EMF non-ionizing radiation run 1.33 times higher risks of contracting childhood cancer compared to those with less than 0.2 µT exposure (95% CI: 1.10, 1.60). The studies were statistically homogeneous (chi-squared P=0.71, I2=0%), and there was no evidence of publication bias. Conclusion: It cannot be concluded that children exposed to non-ionizing radiation have higher risks of childhood cancer compared to those who were not exposed as claimed by the previous reviews. However, concerns about non-ionizing radiation exposure and childhood cancer should not be neglected.
| Item Type: | Article |
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| Keyword: | Non-ionizing radiation, Childhood cancer, Electromagnetic fields, Meta-analysis |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RC Internal medicine ?? RC0254 ?? |
| Department: | FACULTY > Faculty of Medicine and Health Sciences |
| Depositing User: | SITI AZIZAH BINTI IDRIS - |
| Date Deposited: | 10 Mar 2020 09:49 |
| Last Modified: | 16 Apr 2020 23:37 |
| URI: | https://eprints.ums.edu.my/id/eprint/25095 |
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