Phan, Chin Soon and Takashi Kamada and Takahiro Ishii and Toshiyuki Hamada and Charles Santhanaraju Vairappan (2019) Cytotoxic sesquiterpenoids from soft coral Capnella imbricata. Natural Product Communications. pp. 1-4.
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Abstract
A new sesquiterpene, capgermacrene H (1) was isolated together with 7 other compounds, capgermacrenes A-G (2-8), from a population of soft coral Capnella imbricata collected from Mantanani Island, Sabah, Malaysia. The structure of this metabolite was elucidated based on spectroscopic data such as nuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry. Capgermacrene A (2) showed potent cytotoxicity against adult T-cell leukemia, S1T cells at half-maximal inhibitory concentration of 0.79 µg/mL.
| Item Type: | Article |
|---|---|
| Keyword: | Capnella, soft coral, sesquiterpene, capgermacrene H, cytotoxicity, adult T-cell leukemia |
| Subjects: | S Agriculture > SH Aquaculture. Fisheries. Angling |
| Department: | INSTITUTE > Institute for Tropical Biology and Conservation |
| Depositing User: | SITI AZIZAH BINTI IDRIS - |
| Date Deposited: | 02 Jun 2020 16:55 |
| Last Modified: | 02 Jun 2020 16:55 |
| URI: | https://eprints.ums.edu.my/id/eprint/25474 |
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