Toshiyuki Hamada and Yoshito Matsumoto and Phan, Chin Soon and Takashi Kamada and Satoaki Onitsuka and Hiroaki Okamura and Tetsuo Iwagawa and Naomichi Arima and Fumito Tani and Charles S. Vairappan (2019) Aaptamine-related alkaloid from the marine sponge Aaptos aaptos. Natural Product Communications, 4 (9). pp. 1-3.
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Aaptamine-related alkaloid from the marine sponge Aaptos aaptos 1.pdf Download (222kB) | Preview |
Abstract
A new aaptamine-related alkaloid, 1,3-dioxolo [4,5-d] benzo [de]-1,6-naphthyridine (methylenedioxyaaptamine, 1), was isolated from the organic extracts of the Bornean marine sponge Aaptos aaptos, together with a known aaptamine derivative, 8,9,9-trimethoxy-9H-benzo [de]-1,6-naphthyridine (2). The structure of compound 1 was elucidated by interpretation of its spectroscopic data. Two compounds were tested for their cytotoxic potentials against adult T-cell leukemia (ATL) cells, and compound 1 showed moderate cytotoxic potential.
| Item Type: | Article |
|---|---|
| Keyword: | Aaptos aaptos, cytotoxic compound, aaptamine derivatives, marine sponge |
| Subjects: | S Agriculture > SH Aquaculture. Fisheries. Angling |
| Department: | INSTITUTE > Institute for Tropical Biology and Conservation |
| Depositing User: | SITI AZIZAH BINTI IDRIS - |
| Date Deposited: | 02 Jun 2020 16:56 |
| Last Modified: | 02 Jun 2020 16:56 |
| URI: | https://eprints.ums.edu.my/id/eprint/25475 |
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