Nangallenes A and B, halogenated nonterpenoid C15-acetogenins from the Bornean red alga Laurencia nangii

Takashi Kamada and Phan, Chin Soon and Charles Santhanaraju Vairappan (2019) Nangallenes A and B, halogenated nonterpenoid C15-acetogenins from the Bornean red alga Laurencia nangii. Journal of Asian Natural Products Research, 21 (3). pp. 241-247. ISSN 1028-6020 (Print), 1477-2213 (Online)

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Abstract

Two new halogenated nonterpenoids C15-acetogenins, nangallenes A-B (1–2), together with two known halogenated compounds itomanallene A (3) and 2,10-dibromo -3-chloro-α- chamigrene (4), were isolated and identified from the organic extract of the marine red alga Laurencia nangii Masuda collected from the coastal waters in Semporna, Borneo. Their structures were established by means of spectroscopic analysis including IR, high-resolution electrospray ionization mass spectrometry (HRESI-MS), and 1D and 2D NMR techniques. All these metabolites were submitted for the antifungal assay against four species of selected marine fungi. Compounds 1–4 showed potent activity against Haliphthoros sabahensis and Lagenidium thermophilum.

Item Type: Article
Keyword: Laurencia nangii, Rhodomelaceae, red alga, C15-acetogenin, halogenated compound, Borneo
Subjects: S Agriculture > SH Aquaculture. Fisheries. Angling
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Department: INSTITUTE > Institute for Tropical Biology and Conservation
Depositing User: SITI AZIZAH BINTI IDRIS -
Date Deposited: 09 Jun 2020 20:29
Last Modified: 09 Jun 2020 20:29
URI: https://eprints.ums.edu.my/id/eprint/25497

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