Phan, Chin Soon and Takashi Kamada and Takahiro, Ishii and Toshiyuki Hamada and Charles Santhanaraju Vairappan (2019) 12Epi -9deacetoxyxenicin, new cytotoxic diterpenoid from a Bornean soft coral Xenia sp. Natural Product Research, 33 (6). pp. 808-813.
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12-Epi-9-deacetoxyxenicin, new cytotoxic diterpenoid from a Bornean soft coral, Xenia s.pdf Download (45kB) | Preview |
Abstract
One new compound, 12-epi-9-deacetoxyxenicin (1) along with a hydroperoxide product, 12-epi-9-deacetoxy-8-hydroperoxyxenicin (2) and two known sesquiterpenoids (3–4) were isolated from a population of Bornean soft coral Xenia sp. The structures of these secondary metabolites were elucidated based on their spectroscopic data. Compounds 1 and 2 showed cytotoxic activity against ATL cell line, S1T. In addition, compound 3 exhibited hyphal inhibition of Lagenidium thermophilum.
| Item Type: | Article |
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| Keyword: | Soft coral, Xenia sp., xenicane, diterpene, adult T-cell leukemia |
| Subjects: | S Agriculture > SH Aquaculture. Fisheries. Angling ?? SH393_Seagrasses ?? |
| Department: | INSTITUTE > Institute for Tropical Biology and Conservation |
| Depositing User: | SITI AZIZAH BINTI IDRIS - |
| Date Deposited: | 09 Jun 2020 20:30 |
| Last Modified: | 09 Jun 2020 20:30 |
| URI: | https://eprints.ums.edu.my/id/eprint/25498 |
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