Tasnuva ST and Qamar UA and Ghafoor, Kashif and F. Sahena and Md Jahurul Haque Akanda and A. H. Rukshana and M.J.Juliana and Fahad Y. Al-Jalifah and K. C. A. Jalal and Md.Eaqub Ali and I.S.M. Zaidul (2019) α-glucosidase inhibitors isolated from Mimosa pudica L. Natural Product Research, 33 (10). pp. 1495-1499.
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Abstract
The aim of the study was to isolate digestive enzymes inhibitors from Mimosa pudica through a bioassay-guided fractionation approach. Repeated silica gel and sephadex LH 20 column chromatographies of bioactive fractions afforded stigmasterol, quercetin and avicularin as digestive enzymes inhibitors whose IC50 values as compared to acarbose (351.02 ± 1.46 μg mL−1) were found to be as 91.08 ± 1.54, 75.16 ± 0.92 and 481.7 ± 0.703 μg mL−1, respectively. In conclusion, M. pudica could be a good and safe source of digestive enzymes inhibitors for the management of diabetes in future.
| Item Type: | Article |
|---|---|
| Keyword: | Fabaceae, α-glucosidase inhibitors. |
| Subjects: | Q Science > Q Science (General) ?? TP368-456_Food_processing_and_manufacture ?? |
| Department: | FACULTY > Faculty of Food Science and Nutrition |
| Depositing User: | SITI AZIZAH BINTI IDRIS - |
| Date Deposited: | 25 Aug 2020 11:10 |
| Last Modified: | 25 Aug 2020 11:10 |
| URI: | https://eprints.ums.edu.my/id/eprint/25847 |
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