Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View

Mohd Amiruddin Mohd Kassim and Ruziana Masiran and Pang, Nicholas Tze Ping (2021) Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View. Archives of Psychiatry Research, 57. pp. 93-98. ISSN 2671-2008

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Abstract

Introduction and Methods: A man diagnosed with sarcoidosis developed partial retrograde amnesia followed by three months of depressive symptoms with panic attacks, which remitted with an antidepressant and a benzodiazepine. However, three months later hallucinations and overvalued persecutory ideations subsequently emerged, only to show partial response to antipsychotic treatment. Results: Sarcoidosis was treated with corticosteroids but serial thorax imaging shows minimal response. Corticosteroid was onboard throughout treatment, corresponding with non-remission of psychotic symptoms. There are persistent subjective cognitive difficulties but Mini Mental State Exam score is full. He is currently being treated with escitalopram, alprazolam and quetiapine. Conclusion: This case illustrated the dilemma between prolonging the corticosteroid therapy for sarcoidosis treatment and the psychiatric sequalae. While symptomatic antipsychotic treatment is effective, multi-disciplinary approach is imperative in determining the duration of the corticosteroid therapy.

Item Type:	Article
Keyword:	Corticosteroid, Sarcoidosis, Psychosis, Amnesia
Subjects:	R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine
Department:	FACULTY > Faculty of Medicine and Health Sciences
Depositing User:	SITI AZIZAH BINTI IDRIS -
Date Deposited:	05 May 2021 08:35
Last Modified:	05 May 2021 08:35
URI:	https://eprints.ums.edu.my/id/eprint/26901

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