Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient

Zhi, Bryan Yong Yeoh and Vee, Chuan Hoe and Shu, Ning Kong and Wei, Kiat Ooi and Kar, Yee Chiew and Mohd Firdaus Mohd Hayati (2022) Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient. American Journal of Case Reports, 23. pp. 1-6. ISSN 1941-5923

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Abstract

Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and mostly affect the stomach. The size of the tumors vary, ranging from 0.6 cm to 25.5 cm, with a median size of 6.8 cm. Case Report: We report a case of a giant GIST (25×18×8.5 cm) in an 83-year-old woman, which we believe is the largest reported GIST, in Borneo, Malaysia. She presented with gradually increasing abdominal distension with occasional discomfort on movement for 1 month. Computed tomography revealed a large multilobulated enhancing mass measuring 10×20×22 cm with no clear plane with the posterior gastric wall, duodenum, and pancreas. We performed a distal gastrectomy and transverse colon segmentectomy, as the tumor was plastered to the mesentery of the transverse colon. Despite extensive surgery, she recovered well after surgery. Due to her advanced age and the tumor size, a tyrosine kinase inhibitor was not given owing to the possibility of adverse effects. Conclusions: The management of GIST is complicated, especially for a huge GIST with local invasion. Despite the benefits of a tyrosine kinase inhibitor, the role of surgery in managing GIST is crucial, especially for patients with huge tumor size, advanced age, and local complications from the tumor.

Item Type:	Article
Keyword:	Borneo , Case reports , Gastrointestinal stromal tumors , Stomach neoplasms
Subjects:	R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
Department:	FACULTY > Faculty of Medicine and Health Sciences
Depositing User:	SAFRUDIN BIN DARUN -
Date Deposited:	28 Jul 2022 08:08
Last Modified:	28 Jul 2022 08:08
URI:	https://eprints.ums.edu.my/id/eprint/28947

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