Paraneoplastic optic neuropathy secondary to adenocarcinoma of the lung

Yap, Jin Yi and Wan-Hazabbah Wan HItam and Sanihah Abdul Halim and Nurul Ain Masnon (2021) Paraneoplastic optic neuropathy secondary to adenocarcinoma of the lung. BMJ Case Reports, 14. pp. 1-4. ISSN 1757-790X

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Abstract

We describe an uncommon cause of paraneoplastic optic neuropathy in adenocarcinoma of the lung. A 45-year-old healthy woman presented with seizure and encephalitis, followed by an acute visual loss in both eyes for 1 week. Her visual acuity was no perception of light in the right eye and hand movement in the left eye. There was a generalised restriction of extraocular muscle movements in both eyes. Funduscopy showed a bilateral pale optic disc. A paraneoplastic antigen autoimmune profile showed a positive anti-CV2/CRMP-5 antibody. CT of the thorax revealed the presence of right apical lung mass, confirmed to be adenocarcinoma through a biopsy. She was scheduled for lung lobectomy and chemotherapy. Unfortunately, her health deteriorated and she passed away eventually.

Item Type:	Article
Keyword:	Paraneoplastic optic , Neuropathy , Adenocarcinoma , Lung
Subjects:	R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
Department:	FACULTY > Faculty of Medicine and Health Sciences
Depositing User:	SAFRUDIN BIN DARUN -
Date Deposited:	20 Sep 2021 12:11
Last Modified:	20 Sep 2021 12:11
URI:	https://eprints.ums.edu.my/id/eprint/30323

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