Heavy metal biomarker: Fish behaviror, cellular alteration, enzymatic reaction and proteomic approaches

Mohd Khalizan Sabullah and Siti Aqlima Ahmad and Yunus Shukor and Jualang Azlan Gansau and Mohd. Arif Syed and Mohd Rosni Sulaiman and Nor Aripin Shamaan and Jualang (2015) Heavy metal biomarker: Fish behaviror, cellular alteration, enzymatic reaction and proteomic approaches. International Food Research Journal, 22. pp. 435-454. ISSN 1985-4668

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URL: http://www.ifrj.upm.edu.my/22%20(02)%202015/(2).pd...

Abstract

Due to the latest industrial development, many dangerous chemicals have been released directly or indirectly which resulted in the polluted water bodies. Water rehabilitation is an alternative way to restore the quality of water, followed by the environmental management to control the waste discharge to ensure the balance of the degradation rates or detoxifying by environmental factors. However, this process consumed a lot of time and cost. Besides, most of the metal ions, especially copper which is capable to bioaccumulate in aquatic organism and at the elevated level may cause physiological and biochemical alteration which leads to mortality. Environmental monitoring is the initial step presupposed evaluating the potential toxicity of effluent gushing at its purpose to discharge, avoiding the determining effects of contaminant in water bodies. Due to the high sensitivity of the aquatic life towards dissolving toxicant, the fish has been utilized as the biological measurement (Biomarker) to indicate the existence of toxicant exposure and/or the impact towards the evaluation of molecular, cellular to physiological level. Thus, this paper gives an overview of the manipulation of fish as a biomarker of heavy metals through behavior response, hepatocyte alteration, enzymatic reaction and proteomic studies which have proven to be very useful in the environmental pollution monitoring.

Item Type:	Article
Keyword:	Heavy metals , Copper , Behavior , Cellular , Enzyme , Proteomics
Subjects:	Q Science > Q Science (General) > Q1-390 Science (General) S Agriculture > SH Aquaculture. Fisheries. Angling > SH1-691 Aquaculture. Fisheries. Angling > SH20.3-191 Aquaculture > SH151-179 Fish culture
Department:	FACULTY > Faculty of Food Science and Nutrition
Depositing User:	DG MASNIAH AHMAD -
Date Deposited:	19 Nov 2021 10:14
Last Modified:	19 Nov 2021 10:14
URI:	https://eprints.ums.edu.my/id/eprint/30963

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