Domino multicomponent intramolecular cyclization strategy for the multi functionalized Imidazo[1,2-a]pyrimidin-5(1h)-one derivatives

P. R. Khan and G. R. Alugubelli and R. Sireesha and K. Deepti and Pasupuleti Visweswara Rao and M. V. B. Rao (2021) Domino multicomponent intramolecular cyclization strategy for the multi functionalized Imidazo[1,2-a]pyrimidin-5(1h)-one derivatives. Russian Journal of General Chemistry, 91. pp. 1123-1127. ISSN 1070-3632 (P-ISSN) , 1608-3350 (E-ISSN)

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Abstract

A microwave assisted novel domino synthetic approach to trifluoromethyl substituted imidazo[1,2-a]pyrimidin-5(1H)-one derivatives has been developed via a multi component cascade strategy in a single operation. The synthesized compounds can find application as structural components of biologically active compounds.

Item Type: Article
Keyword: Guanidine , Propargyl bromide , Domino reaction , Intramolecular cyclization , Imidazo[1,2-a]pyrimidin-5(1H)-one
Subjects: Q Science > QD Chemistry > QD1-999 Chemistry > QD241-441 Organic chemistry
Department: FACULTY > Faculty of Medicine and Health Sciences
Depositing User: SAFRUDIN BIN DARUN -
Date Deposited: 24 Nov 2021 08:06
Last Modified: 24 Nov 2021 08:06
URI: https://eprints.ums.edu.my/id/eprint/31189

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