Immune System in COVID-19: Is It Temporarily Defeated While Conquering?

Aye Aye Wynn and Nang Khin Mya and Tin Tin Thein (2022) Immune System in COVID-19: Is It Temporarily Defeated While Conquering? Borneo Journal of Medical Sciences, 16. pp. 21-29. ISSN 1985-1758 (P-ISSN) , 2710-7353 (E-ISSN)

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Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is spreading worldwide and becomes a major cause of mortality. In addition to major pathology in lungs such as pneumonia or respiratory failure, multiorgan failure and frequently haematological disorders such as thromboembolic manifestations are leading causes of mortality. This study reviews the interaction of the immune system with target cells, the role of cytokines and other components such as complements encountered in the pathophysiology of major disease processes and possible post-recovery complications. Although there are some clinical effects induced by strong immune reactions, long term immunity against the virus is found in the majority.

Item Type: Article
Keyword: COVID-19 , Immune system , Thrombosis , Cytokine storm , Macrophage activation syndrome
Subjects: R Medicine > R Medicine (General) > R5-920 Medicine (General)
R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA421-790.95 Public health. Hygiene. Preventive medicine
Department: FACULTY > Faculty of Medicine and Health Sciences
Depositing User: SITI AZIZAH BINTI IDRIS -
Date Deposited: 08 Jun 2022 09:47
Last Modified: 08 Jun 2022 09:47
URI: https://eprints.ums.edu.my/id/eprint/32653

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