A rare case of breast squamous cell carcinoma and literature review

Bhirrinta Varughese and Siti Zubaidah Sharif and Yee, Ho Kah and Nik Amin Sahid Nik Lah (2022) A rare case of breast squamous cell carcinoma and literature review. Annals of Medicine and Surgery, 78. pp. 1-3. ISSN 2049-0801

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Abstract

Introduction: Breast Squamous Cell Carcinoma (SCC) is quite a rare tumor that the features portray squamous cell differentiation. Presentation of case: We report a case of a 56-year-old female presented left breast lump that had been increasing in size for a 7 months duration associated with nipple retraction for one week. Ultrasound breast was done and revealed a large mixed echo density mass lesion in the left breast at 12 o’clock, 2cm from the nipple and measuring 4.2 × 3.4cm along with an enlarged node in the left axilla with thickened cortex and as for Mammogram revealed suspicious left breast lesion with enlarged axillary nodes, BIRADS 5. Histopathology from the left breast showed Invasive carcinoma with squamous differentiation, B5b, ER: negative, PR: Positive, Her2: Negative, CK5/6: Positive. Then a staging CECT Thorax, Abdomen and Pelvis was done which showed enhancing mass lesion seen at the left breast (4.1 × 4.3cm) with areas of necrosis within and multiple enlarged left axillary nodes seen with no local infiltration to the muscle or skin as well as no distant metastases. Patient underwent Neoadjuvant chemotherapy for 6 cycles and completed them. Discussion: This case highlights the crucial need of early detection along with the obstacles faced in reaching an early diagnosis tagged with the lack of guideline to manage this patient. Conclusion: In the management of Breast Squamous Cell Carcinoma, the standard treatment would be to go for mastectomy with axillary clearance. However, the prognosis usually depends on the tumor size and the advance age of the patient as described in this article.

Item Type:	Article
Keyword:	Breast cancer , Squamous , Metaplastic
Subjects:	R Medicine > RC Internal medicine > RC31-1245 Internal medicine > RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
Department:	FACULTY > Faculty of Medicine and Health Sciences
Depositing User:	SAFRUDIN BIN DARUN -
Date Deposited:	15 Aug 2022 09:39
Last Modified:	15 Aug 2022 09:39
URI:	https://eprints.ums.edu.my/id/eprint/33750

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