Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii

Chan, Pei Teng and Patricia @ Patricia Clementina Matanjun and Suhaimi Md. Yasir and Djuli Acun Darmawan @ Tan Tek Song (2013) Antioxidant and hypolipidaemic properties of red seaweed, Gracilaria changii. Journal of Applied Phycology, 26. pp. 987-997. ISSN 0921-8971 (P-ISSN) , 1573-5176 (E-ISSN)

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Abstract

The edible red seaweed, Gracilaria changii, was collected from the coastal area of Sarawak, Malaysia, and evaluated for its hypolipidaemic properties using high cholesterol/high fat (HF) induced male Sprague–Dawley rats. In the in vivo study, the HF diet group showed significantly higher total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), atherogenic index (AI) and body weight gain as compared to other treatment groups. At the end of treatment period, rats fed with a HF diet supplemented with 5 % freeze-dried G. changii powder had significantly reduced plasma TC (−39.19 %), LDL-C (−36.36 %), and triglycerides (TG) content (− 25.45 %). Meanwhile, 10 % seaweed powder significantly lowered the plasma TC, LDL-C and TG content by −40.34, −35.95 and −30.91 % respectively, compared to the HF group. The AI of rats supplemented with 10 % seaweed powder was the lowest among the treatment groups and indicates a lowered risk for cardiovascular diseases. The plasma lipid peroxidation of the seaweed powder-fed groups was also significantly lower than the HF group, while the erythrocyte enzyme antioxidant activities of superoxide dismutase, catalase and glutathione peroxidase of the treatment groups were also improved. Diets supplemented with seaweed powder also decreased plasma aspartate aminotransferase and the alanine aminotransferase levels.

Item Type: Article
Keyword: Rhodophyta , Gracilaria , Body weight , Dietary fibre , Enzyme antioxidants , Hypercholesterolaemic , Lipid peroxidation , Lipid profile
Subjects: Q Science > QK Botany > QK1-989 Botany
T Technology > TX Home economics > TX1-1110 Home economics > TX341-641 Nutrition. Foods and food supply
Department: FACULTY > Faculty of Food Science and Nutrition
Depositing User: SAFRUDIN BIN DARUN -
Date Deposited: 15 Sep 2022 16:06
Last Modified: 15 Sep 2022 16:06
URI: https://eprints.ums.edu.my/id/eprint/34131

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